Carbon dioxide hold-up as a source of error in batch-culture calculations
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چکیده
منابع مشابه
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Oxygen supply and dissolved carbon dioxide (dCO(2)) stripping are two of the most important control parameters in cell culture. In this study, we investigated the effect of scale-up on the volumetric gas transfer coefficient with bioreactors of different sizes (working volume: 80 L, 500 L, 2000 L, and 10,000 L; aspect ratio: 1.0-1.6). Sparging air into water increased the volumetric oxygen tran...
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ژورنال
عنوان ژورنال: Biotechnology and Bioengineering
سال: 1980
ISSN: 0006-3592,1097-0290
DOI: 10.1002/bit.260220914